TECHNOLOGY

HARNESSING STEM CELLS FOR REGENERATIVE MEDICINE

Since its discovery, stem cells have been extensively studied. Due to their unique ability to differentiate and potential for unlimited proliferation, researchers have began to discover many therapeutic uses for them. Basically, stem cells are like the raw material of the body whereby all the other cells with specialised functions are generated from.

Perinatal Stem Cells

  • Found in amniotic fluid and membrane, cord blood
  • Similar to embryonic cells but with fewer ethical issues

Induced Pluripotent Stem Cells

  • Regular adult cells genetically transformed into stem cells
  • Readily available
  • Can avoid immune rejection

Embryonic Stem Cells

  • From embryo (blastocyst)
  • Pluripotent
  • Regenerative properties

Adult Stem Cells

  • Found in small quantity in bone marrow and adipose
  • Limited cell differentiation
  • Invasive extraction
The therapeutic potential of stem cells is largely mediated by paracrine factors (cytokines and growth factors, signaling lipids, mRNAs, and regulatory miRNAs) that are released extracellularly through exosomes, forming the >Essence of Stem Cells”.

OUR TECHNOLOGY

In StemiGen Therapeutics, we leverages on the highly regenerative ability of mesenchymal stem cells (MSCs) isolated from the umbilical cord and induced pluripotent MSC, together with defined exosomal extracts in proprietary formulations to aid healing of chronic wounds and for therapeutics. Isolation of stem cells and production are done locally under cGMP environment.

STEM CELL BASED WOUND HEALING CLINICAL TRIAL IN SINGAPORE

Working with our collaborators in KK Women’s & Children’s Hospital (KKH), National University Hospital (NUH) and clinics in Novena Medical Centre, we aim to conduct the first successful stem cell based wound healing clinical trial in Singapore.

We strive to achieve

  1. Complication-free wound healing
  2. Shortened time for recovery
  3. Quality and Safe
  4. Lower treatment cost to benefit the mass
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